Fleet, George W J : rechercher sur Z-Library

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1

Iminosugars as therapeutic agents: recent advances and promising trends

Nash, Robert J, Kato, Atsushi, Yu, Chu-Yi, Fleet, George WJ

Journal:

Future Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 946 KB

english, 2011

2

Kiliani reactions on ketoses: branched carbohydrate building blocks from D-tagatose and D-psicose

Raquel Soengas, Ken Izumori, Michela Iezzi Simone, David J. Watkin, Ulla P. Skytte, Wim Soetaert, George W.J. Fleet

Journal:

Tetrahedron Letters

Année:

2005

Langue:

english

Fichier:

PDF, 149 KB

english, 2005

3

Homonojirimycin analogues and their glucosides from Lobelia sessilifolia and Adenophora spp. (Campanulaceae)

Kyoko Ikeda, Megumi Takahashi, Makoto Nishida, Miwa Miyauchi, Haruhisa Kizu, Yukihiko Kameda, Munehisa Arisawa, Alison A. Watson, Robert J. Nash, George W.J. Fleet, Naoki Asano

Journal:

Carbohydrate Research

Année:

1999

Langue:

english

Fichier:

PDF, 122 KB

english, 1999

4

Polyhydroxylated pyrrolidine and piperidine alkaloids from Adenophora triphylla var. japonica (Campanulaceae)

Naoki Asano, Makoto Nishida, Miwa Miyauchi, Kyoko Ikeda, Masaru Yamamoto, Haruhisa Kizu, Yukihiko Kameda, Alison A. Watson, Robert J. Nash, George W.J. Fleet

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 114 KB

english, 2000

5

Some comments on an allegedly “facile synthesis of nojirimycin”

George W.J Fleet, Nigel G Ramsden, Neil M Carpenter, Sigthor Peturssona, Robin T Aplin

Journal:

Tetrahedron Letters

Année:

1990

Langue:

english

Fichier:

PDF, 291 KB

english, 1990

6

Spirodiketopiperazines of mannofuranose: carbopeptoid α-amino acid esters at the anomeric position of mannofuranose

Juan C Estevez, Jonathan W Burton, Ramon J Estevez, Helen Ardron, Mark R Wormald, Raymond A Dwek, David Brown, George W.J Fleet

Journal:

Tetrahedron: Asymmetry

Année:

1998

Langue:

english

Fichier:

PDF, 349 KB

english, 1998

7

Mimics of l-rhamnose: Anomeric spirohydantoins and diketopiperazines-approaches to novel N-linked glycopeptides of rhamnofuranose

Juan C. Estevez, Martin D. Smith, Alexandra L. Lane, Sarah Crook, David J. Watkin, Gurdyal S. Besra, Patrick J. Brennan, Robert J. Nash, George W.J. Fleet

Journal:

Tetrahedron: Asymmetry

Année:

1996

Langue:

english

Fichier:

PDF, 227 KB

english, 1996

8

Ring-Chain Tautomerism in Organic Synthesis: Synthesis of Heterocyclic Enamines from a Novel and Practical Formal Ring Transformation Reaction of Lactones

Wang, Mei-Xiang, Liu, Yong, Gao, Hong-Yun, Zhang, Yan, Yu, Chu-Yi, Huang, Zhi-Tang, Fleet, George W. J.

Journal:

Journal of Organic Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 87 KB

english, 2003

9

Glycosidase Inhibition by All 10 Stereoisomeric 2,5-Dideoxy-2,5-iminohexitols Prepared from the Enantiomers of Glucuronolactone

Ayers, Benjamin J., Ngo, Nigel, Jenkinson, Sarah F., Martínez, R. Fernando, Shimada, Yousuke, Adachi, Isao, Weymouth-Wilson, Alexander C., Kato, Atsushi, Fleet, George W. J.

Journal:

Journal of Organic Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.83 MB

english, 2012

10

Isolation of Glycosidase-Inhibiting Hyacinthacines and Related Alkaloids from Scilla socialis

Kato, Atsushi, Kato, Noriko, Adachi, Isao, Hollinshead, Jackie, Fleet, George W. J., Kuriyama, Chinami, Ikeda, Kyoko, Asano, Naoki, Nash, Robert J.

Journal:

Journal of Natural Products

Année:

2007

Langue:

english

Fichier:

PDF, 86 KB

english, 2007

11

New Polyhydroxylated Pyrrolidine, Piperidine, and Pyrrolizidine Alkaloids from Scilla s ibirica

Yamashita, Toru, Yasuda, Kayo, Kizu, Haruhisa, Kameda, Yukihiko, Watson, Alison A., Nash, Robert J., Fleet, George W. J., Asano, Naoki

Journal:

Journal of Natural Products

Année:

2002

Langue:

english

Fichier:

PDF, 227 KB

english, 2002

12

Looking-Glass Synergistic Pharmacological Chaperones: DGJ and L-DGJ from the Enantiomers of Tagatose

Jenkinson, Sarah F., Fleet, George W. J., Nash, Robert J., Koike, Yuriko, Adachi, Isao, Yoshihara, Akihide, Morimoto, Kenji, Izumori, Ken, Kato, Atsushi

Journal:

Organic Letters

Année:

2011

Langue:

english

Fichier:

PDF, 709 KB

english, 2011

13

Nitrogen-Containing Furanose and Pyranose Analogues from Hyacinthus orientalis

Asano, Naoki, Kato, Atsushi, Miyauchi, Miwa, Kizu, Haruhisa, Kameda, Yukihiko, Watson, Alison A., Nash, Robert J., Fleet, George W. J.

Journal:

Journal of Natural Products

Année:

1998

Langue:

english

Fichier:

PDF, 110 KB

english, 1998

14

Tetrahydrofuran amino acids—versatile building blocks for unnatural biopolymers: lack of secondary structure in oligomeric carbopeptoids derived from a D-galacto-5-(aminomethyl) tetrahydrofuran-2-carboxylic acid

Brittain, Dominic E. A., Watterson, Mark P., Claridge, Timothy D. W., Smith, Martin D., Fleet, George W. J.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

2000

Langue:

english

Fichier:

PDF, 303 KB

english, 2000

15

Secondary structure in oligomers of carbohydrate amino acids

Smith, Martin D., Claridge, Timothy D. W., Fleet, George W. J., Tranter, George E., Sansom, Mark S. P.

Journal:

Chemical Communications

Année:

1998

Langue:

english

Fichier:

PDF, 145 KB

english, 1998

16

Evaluation Outcomes Resulting from an Internet-Based Continuing Professional Development (CPD) Asthma Program: Its Impact on Participants' Knowledge and Satisfaction

Fleet, Lisa J., Fox, George, Kirby, Fran, Whitton, Cindy, McIvor, Andrew

Journal:

Journal of Asthma

Année:

2011

Langue:

english

Fichier:

PDF, 134 KB

english, 2011

17

LETTERS

Louis Pizzitola, Thomas Schatz, Dorothy Burgess, George Rafael and Sam Van Fleet

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 317 KB

english, 2002

18

Iminosugar idoBR1 Isolated from Cucumber Cucumis sativus Reduces Inflammatory Activity

Nash, Robert J., Bartholomew, Barbara, Penkova, Yana B., Rotondo, Dino, Yamasaka, Fernanda, Stafford, Graham P., Jenkinson, Sarah F., Fleet, George W. J.

Journal:

Année:

2020

Fichier:

PDF, 1.97 MB

2020

19

Designing secondary structures: 5-azidomethyl tetrahydrofuran-2-carboxylates as carbohydrate-derived dipeptide isosteres

Martin D. Smith, George W. J. Fleet

Journal:

Journal of Peptide Science

Année:

1999

Langue:

english

Fichier:

PDF, 1.13 MB

english, 1999

20

Synthesis and Biological Characterisation of Novel N-Alkyl-Deoxynojirimycin α-Glucosidase Inhibitors

Amy J. Rawlings, Hannah Lomas, Adam W. Pilling, Marvin J.-R. Lee, Dominic S. Alonzi, J. S. Shane Rountree, Sarah F. Jenkinson, George W. J. Fleet, Raymond A. Dwek, John H. Jones, Terry D. Butters

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 214 KB

english, 2009

21

ChemInform Abstract: Intermediates for Incorporation of Tetrahydroxypipecolic Acid Analogues of α- and β-D-Mannopyranose into Combinatorial Libraries: Unexpected Nanomolar-Range Hexosaminidase Inhibitors. Synthesis of α- and β-Homomannojirimycin.

John P. Shilvock, Robert J. Nash, Janet D. Lloyd, Ana L. Winters, Naoki Asano, George W. J. Fleet

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 38 KB

english, 1999

22

ChemInform Abstract: Synthesis of an Eight-Carbon Homologue of α-Homomannojirimycin via a Bicyclic Aminolactone.

John P. Shilvock, Kenneth Y. Hsia, Robert J. Nash, Janet D. Lloyd, Ana L. Winters, Naoki Asano, George W. J. Fleet

Journal:

Année:

1999

Fichier:

PDF, 33 KB

1999

23

ChemInform Abstract: Professor George W. J. Fleet. Recipient of the RSC Haworth Lectureship.

George W. J. Fleet

Journal:

Année:

1999

Fichier:

PDF, 25 KB

1999

24

ChemInform Abstract: Tetrazoles of Manno- and Rhamnofuranoses.

Benjamin G. Davis, Robert J. Nash, Alison A. Watson, Colin Smith, George W. J. Fleet

Journal:

Année:

1999

Fichier:

PDF, 29 KB

1999

25

ChemInform Abstract: Open-Chain Acetonides of D-Galactono-1,4-lactone as Starting Materials for Pyrrolidines, Azepanes and 5-Azidomethyltetrahydrofuran-2-carboxylates: Monomers for Polyhydroxylated Nylon and for Tetrahydrofuran Carbopeptoids.

Daniel D. Long, Rebecca J. E. Stetz, Robert J. Nash, Daniel G. Marquess, Janet D. Lloyd, Ana L. Winters, Naoki Asano, George W. J. Fleet

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 37 KB

english, 1999

26

ChemInform Abstract: Tetrahydrofuran α-Azido Esters: Precursors of Anomeric α-Amino Acid Monomers via Radical Bromination.

Martin D. Smith, Daniel D. Long, Angeles Martin, Neil Campbell, Yves Bleriot, George W. J. Fleet

Journal:

Année:

1999

Fichier:

PDF, 31 KB

1999

27

ChemInform Abstract: 3-Azidotetrahydrofuran-2-carboxylates: Monomers for Five-Ring Templated α-Amino Acid Foldamers?

Mark P. Watterson, Lea Pickering, Martin D. Smith, Sarah J. Hudson, Paul R. Marsh, Jacqueline E. Mordaunt, David J. Watkin, Christopher J. Newman, George W. J. Fleet

Journal:

Année:

1999

Fichier:

PDF, 32 KB

1999

28

ChemInform Abstract: Synthesis of Bis(1,3-dihydroxy-isopropyl)amine by Reductive Amination of Dihydroxyacetone: Open Chain Equivalent of DMDP and a Potential AB4 Dendritic Monomer.

David A. Scott, Thomas M. Kruelle, Malcolm Finn, Robert J. Nash, Ana L. Winters, Naoki Asano, Terry D. Butters, George W. J. Fleet

Journal:

Année:

2000

Fichier:

PDF, 33 KB

2000

29

ChemInform Abstract: Synthesis of Homorhamnojirimycins (I) and Related Trihydroxypipecolic Acid Derivatives (II) and (III) via Divergent Bicyclic Amino Lactone Intermediates: Inhibition of Naringinase (L-Rhamnosidase) and dTDP-Rhamnose Biosynthesis.

John P. Shilvock, Joseph R. Wheatley, Robert J. Nash, Alison A. Watson, Rhodri C. Griffiths, Terry D. Butters, Mathias Mueller, David J. Watkin, David A. Winkler, George W. J. Fleet

Journal:

Année:

2000

Fichier:

PDF, 29 KB

2000

30

ChemInform Abstract: Piperidine Analogues of D-Galactose as Potent Inhibitors of α-Galactosidase: Synthesis by Stannane-Mediated Hydroxymethylation of 5-Azido-1,4-lactones. Structural Relationships Between D-Galactosidase and L-Rhamnosidase Inhibitors.

John P. Shilvock, Robert J. Nash, Alison A. Watson, Ana L. Winters, Terry D. Butters, Raymond A. Dwek, David A. Winkler, George W. J. Fleet

Journal:

Année:

2000

Fichier:

PDF, 31 KB

2000

31

ChemInform Abstract: Designing Secondary Structures: 5-Azidomethyl Tetrahydrofuran-2- Carboxylates as Carbohydrate-derived Dipeptide Isosteres

Martin D. Smith, George W. J. Fleet

Journal:

Année:

2000

Fichier:

PDF, 26 KB

2000

32

ChemInform Abstract: New Polyhydroxylated Pyrrolizidine Alkaloids from Muscari armeniacum: Structural Determination and Biological Activity.

Naoki Asano, Hiroyo Kuroi, Kyoko Ikeda, Haruhisa Kizu, Yukihiko Kameda, Atsushi Kato, Isao Adachi, Alison A. Watson, Robert J. Nash, George W. J. Fleet

Journal:

Année:

2000

Fichier:

PDF, 31 KB

2000

33

ChemInform Abstract: Sugar-Mimic Glycosidase Inhibitors: Natural Occurrence, Biological Activity, and Prospects for Therapeutic Application

Naoki Asano, Robert J. Nash, Russell J. Molyneux, George W. J. Fleet

Journal:

Année:

2000

Fichier:

PDF, 27 KB

2000

34

ChemInform Abstract: Modification of Glycosylation as a Therapeutic Strategy

Bryan Winchester, George W. J. Fleet

Journal:

Année:

2000

Fichier:

PDF, 25 KB

2000

35

ChemInform Abstract: Tetrahydrofuran Amino Acids — Versatile Building Blocks for Unnatural Biopolymers: Lack of Secondary Structure in Oligomeric Carbopeptoids Derived from a D-galacto-5-(aminomethyl)tetrahydrofuran-2-carboxylic Acid.

Dominic E. A. Brittain, Mark P. Watterson, Timothy D. W. Claridge, Martin D. Smith, George W. J. Fleet

Journal:

Année:

2001

Fichier:

PDF, 26 KB

2001

36

ChemInform Abstract: Tetrahydrofuran Amino Acids: Secondary Structure in Tetrameric and Octameric Carbopeptoids Derived from a D-allo 5-(Aminomethyl)tetrahydrofuran-2-carboxylic Acid.

Natasha L. Hungerford, Timothy D. W. Claridge, Mark P. Watterson, Robin T. Aplin, Andres Moreno, George W. J. Fleet

Journal:

Année:

2001

Fichier:

PDF, 26 KB

2001

37

ChemInform Abstract: Tetrahydrofuran Amino Acids: β- and γ-Azidotetrahydrofurancarboxylic Acid Monomers Derived from D-Glucoheptonolactone as Building Blocks for β- and γ-Oligopeptides.

Natasha L. Hungerford, George W. J. Fleet

Journal:

Année:

2001

Fichier:

PDF, 28 KB

2001

38

ChemInform Abstract: Polyhydroxylated Alkaloids — Natural Occurrence and Therapeutic Applications

Alison A. Watson, George W. J. Fleet, Naoki Asano, Russell J. Molyneux, Robert J. Nash

Journal:

Année:

2001

Fichier:

PDF, 25 KB

2001

39

ChemInform Abstract: Carbopeptoids: Peptides and Diketopiperazines Incorporating the Anomeric Centre of Mannopyranose.

Daniel D. Long, Richard J. Tennant-Eyles, Juan C. Estevez, Mark R. Wormald, Raymond A. Dwek, Martin D. Smith, George W. J. Fleet

Journal:

Année:

2001

Fichier:

PDF, 32 KB

2001

40

ChemInform Abstract: cis- and trans-3-Azido-oxetane-2-carboxylate Scaffolds: Hexamers of Oxetane cis-β-Amino Acids.

Sarah F. Barker, Donald Angus, Claude Taillefumier, Michael R. Probert, David J. Watkin, Mark P. Watterson, Timothy D. W. Claridge, Natasha L. Hungerford, George W. J. Fleet

Journal:

Année:

2002

Fichier:

PDF, 33 KB

2002

41

Complex Tetrahydrofurans from Carbohydrate Lactones: THF Amino Acids as Building Blocks for Unnatural Biopolymers.

Daniel D. Long, Martin D. Smith, Angeles Martin, Joseph R. Wheatley, David G. Watkin, Mattaius Mueller, George W. J. Fleet

Journal:

Année:

2003

Fichier:

PDF, 320 KB

2003

42

Ring-Chain Tautomerism in Organic Synthesis: Synthesis of Heterocyclic Enamines from a Novel and Practical Formal Ring Transformation Reaction of Lactones.

Mei-Xiang Wang, Yong Liu, Hong-Yun Gao, Yan Zhang, Chu-Yi Yu, Zhi-Tang Huang, George W. J. Fleet

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 216 KB

english, 2003

43

Huge (14-, 21-, 28-, 35-, 56- and 70-Membered Ring) Macrocyclic Lactams — A Novel Family of Carbopeptoid-Cyclodextrins.

Benjamin A. Mayes, Lieven Simon, David J. Watkin, Christopher W. G. Ansell, George W. J. Fleet

Journal:

Année:

2004

Fichier:

PDF, 73 KB

2004

44

Mixed Sugar—Nylon 14-, 28- and 42-Membered Ring Macrocyclic Lactams.

Benjamin A. Mayes, Andrew R. Cowley, Christopher W. G. Ansell, George W. J. Fleet

Journal:

Année:

2004

Fichier:

PDF, 70 KB

2004

45

An Approach to the Generation of Simple Analogues of the Antitumor Agent Spicamycin.

Stephane Mons, George W. J. Fleet

Journal:

Année:

2004

Fichier:

PDF, 129 KB

2004

46

Cyclo[(6-amino-6-deoxy-D-galactonic acid)4]: A New Class of Carbopeptoid-Cyclodextrin.

Benjamin A. Mayes, Rebecca J. E. Stetz, Christopher W. G. Ansell, George W. J. Fleet

Journal:

Année:

2004

Fichier:

PDF, 69 KB

2004

47

A Direct Retro-Reformatsky Fragmentation: Formal Ring Enlargement of Cyclic Ketones for Novel and Practical Synthesis of Heterocyclic Enamines.

Mei-Xin Zhao, Mei-Xiang Wang, Chu-Yi Yu, Zhi-Tang Huang, George W. J. Fleet

Journal:

Année:

2004

Fichier:

PDF, 164 KB

2004

48

Looking Glass Inhibitors: L-DMDP, a More Potent and Specific Inhibitor of α-Glucosidases than the Enantiomeric Natural Product DMDP.

Chu-Yi Yu, Naoki Asano, Kyoko Ikeda, Mei-Xiang Wang, Terry D. Butters, Mark R. Wormald, Raymond A. Dwek, Ana L. Winters, Robert J. Nash, George W. J. Fleet

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 25 KB

english, 2005

49

ChemInform Abstract: Synthesis and Glycosidase Inhibition of the Enantiomer of (-)-Steviamine, the First Example of a New Class of Indolizidine Alkaloid.

Xiang-Guo Hu, Barbara Batholomew, Robert J. Nash, Francis X. Wilson, George W. J. Fleet, Shinpei Nakagawa, Atsushi Kato, Yue-Mei Jia, Renate van Well, Chu-Yi Yu

Journal:

Année:

2010

Fichier:

PDF, 18 KB

2010

50

ChemInform Abstract: Oxetanes from the Ring Contraction of α-Triflates of γ-Lactones: Oxetane Nucleosides and Oxetane Amino Acids

Sarah F. Jenkinson, George W. J. Fleet

Journal:

Année:

2011

Fichier:

PDF, 19 KB

2011